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It ended the dominance of the Bison on the American plains. By so doing, it broke the Indians capacity to survive and sent them onto reservations.
My dad had a 45-70 Government version of the Sharps. I shot it when I was about 12 years old and it kicked like a wild mule. Dad traded it for a custom 1911 from Wilson's Gun Shop just before it became Wilson Combat.
The last bolt gun I built I almost used a set trigger, used a Timney instead.